Research related to pain management has brought national attention to a Northeast Ohio Medical University team. Mate Soric, Pharm.D., associate professor of pharmacy practice and vice chair for practice-based research, and Rachel Neugebauer, Pharm.D. (’19) were part of a team whose recent study demonstrated a clinically relevant decrease in the efficacy of tramadol when used for pain control in patients receiving a strong CYP2D6 inhibitor. The results might encourage clinicians to review medication lists for this interaction and adjust regimens accordingly to ensure adequate pain control.
MSN Lifestyle writes, “If you’re a chronic pain patient who’s ever been told you’re “just a drug-seeker” when say your pain meds aren’t working, a new study about the opioid tramadol might explain why the medication is less effective for some. An interaction between tramadol and specific types of popular antidepressants prevent tramadol from working correctly.”
Read the study in the American College of Clinical Pharmacy’s Pharmacotherapy Journal.