- Professor of Physiology
- Chief Scientist, Crystal Diagnostics, Ltd
The majority of my early research related to pulmonary pathophysiology secondary to smoke inhalation, hemorrhage, Blunt trauma, or sepsis. In the early 2000’s, I established a multidisciplinary research focus group to collaboratively developed a liquid crystal based pathogen detection technology. That technology, with 15 related patents, is the basis for our development start-up company, Crystal Diagnostics Ltd. I am the Chief Scientist for the company and my research interest now focus on use of that technology to detect human pathogens.
Area of Expertise/Research Interests
Our current research relates to detection of microbial pathogens in various food matrices. Additional studies have demonstrated the capacity of the technology to detect the Ebola virus.
- Ph.D., Physiology, University of Wisconsin- Madison, 1977
- M.S., Dairy Husbandry, University of Missouri-Columbia, 1967
- B.S., Dairy Physiology, University of Missouri-Columbia, 1965
- Course Director, “Physiological Basis of Medicine”
Academic & Professional Activities
- Reviewer for Chemistry and Physics of Lipids
- Reviewer for Clinical and Vaccine Immunology (CVI)
- FlexMatters Advisory Committee, Nortech
- Reviewer for Deployment Related Medical Research Program (Department of Defense Program)
- Weidong Zhao, Curtis H. Stumpf, Karl Devlin, Gary D. Niehaus. Biogeographic patterns of Escherichia coli, Enterococcus spp., and Bacteroidales fecal indicator bacteria at a Villa Angela and Euclid Creek Beach, Ohio. 2014 Water Microbiology Conference, May 5, 2014, Chapel Hill, NC.
- Weidong Zhao, Curtis H. Stumphy, Brian Bullard, Stephanie Kuzinko, Gary D. Niehaus. Rapid, Multiplexed detection of Shiga toxin producing E. coli using a liquid crystal based immune assay. International Association of Food Protection. July 25-28, Portland Oregon
- Brian Bullard, Curtis H. Stumpf, Weidong Zhao, Stephanie Kuzinko, Gary D. Niehaus. Development of a Liquid Crystal-based Salmonella detection assay. International Association of Food Protection. July 25-28, Portland Oregon
- C. H. Stumpf, B. Bullard, W. Zhao, S. Kuzenko and G.D. Niehaus, ‘Rapid Detection of Listeria Monocytogenes Using a Liquid Crystal-Based Immunoassay’, 2016, International Association of FD.
- C. H. Stumpf, B. Bullard, S. Kuzenko, E. Rusnak and G.D. Niehaus. Detection of E. coli O157:H7 and Salmonella in Cannabis and a Cannabis Simulant using a Liquid Crystal-based Immunoassay. International Association of Food Protection, July 16 – 18, 2017, Tampa, FL
- Outstanding Faculty Research Award (2008)
- Eight patents
- Niehaus, G.D. and S.R. Mehendale, Quantifying rat pulmonary intravascular mononuclear phagocytes. Anatomical Record 252:626-636, 1998
- Niehaus, GD, A Patel , K Khanna , VW Vanek and DL Fagan. Circadian rhythm in cell adhesion molecule expression by normal human leukocytes. Can J Physiol Pharmacol, 80:935-940, 2002
- Shiyanovskii, S. V., T. Schneider, I. I. Smalyukh, T. Ishikawa, G. D. Niehaus, K. J. Doane, C. J. Woolverton, and O. D. Lavrentovich. Real-time microbe detection based on director distortions around growing immune complexes in lyotropic chromonic liquid crystals. Physical Review E 71, 020702® ( 2005)
- Curtis H. Stumpf, Weidong Zhao, Brian Bullard, and Gary D. Niehaus. Crystal Diagnostics Xpress™ E7 STEC for the Rapid Multiplex Detection of E. coli O157 and non-O157 Shiga toxin-producing E. coli is Granted PTM Status. Inside Laboratory Management July/Aug(2015)
- Brian Bullard, Curtis H. Stumpf, Weidong Zhao, Stephanie Kuzenko, and Gary D. Niehaus. ‘Crystal Diagnostics Xpress S Kit for the rapid detection of Salmonella in selected food Matrixes’, (2017) Journal of AOAC International 100:1038-1050 (2017)