Academic Title(s)

• Associate Professor, Department of Integrative Medical Sciences

Administrative Title(s)

• Chair, Radiation Safety Committee

Bio

Dr. Yoon-Kwang Lee is a faculty member at NEOMED, College of Medicine, Department of Integrative Medical Sciences. Dr. Lee received a Ph.D. from the Rutgers University, New Brunswick, New Jersey. He did a postdoctoral training at Harvard Medical School and at Baylor College of Medicine. Prior to joining NEOMED, he was an Assistant Professor at Baylor College of Medicine. He is currently a member of the American Association for the Study of Liver Diseases, the American Diabetes Association, and the American Physiology Society and serves as an Editorial Board member for International Journal of Cardiology.

Area of Expertise/Research Interests

• Physiological function of the orphan nuclear hormone receptor SHP in metabolic homeastasis
• Role of a novel transcriptional repressor Hes6 in non-alcoholic fatty liver diseases

Educational Background

• Ph.D., Microbiology and Molecular Genetics, Rutgers University, 1995
• M.S., Biotechnology, Yonsei University, Korea, 1987
• B.S., Food Engineering, Yonsei University, Korea, 1985

Courses

• Molecules to Cells

Academic & Professional Activities

• American Association for the Study of Liver Diseases
• American Diabetes Association
• American Physiology Society
• Editorial Board member: International Journal of Cardiology

Publications

• Park JE, Lee M, Kim SC, Zhang Y, Hardwick JP, and Lee, YK. 2017. Hairy and Enhancer Split 6 prevents hepatic lipid accumulation through inhibition of Pparg2 expression. Hepatology Communications. 1:1085-1098
• Akinrotimi O, Riessen R, VanDuyne P, Park JE, Lee YK, Wong LJ, Zavacki AM, Schoonjans K, Anakk S. 2017. Shp deletion prevents hepatic steatosis and when combined with Fxr loss protects against type 2 diabetes. Hepatology. 66(6): 1854-1865
• Palmisano BT, Le TD, Zhu L, Lee YK, and Stafford JM. 2016. Cholesteryl ester transfer protein alters liver and plasma triglyceride metabolism through two liver networks in female mice. J Lipid Res. 57(8):1541-1551
• Park JE, Lee M, Mifflin R, and Lee, YK. 2016. Enhanced ethanol catabolism in orphan nuclear receptor SHP-null mice. Am J Physiol Gastrointest Liver Physiol. 310(10):G799-807
• Kim SC, Kim C, Axe D, Cook A, Lee M, Li T, Smallwood N, Chiang JYL, Hardwick JP, Moore DD, Lee YK. 2013. All-trans-retinoic acid ameliorates hepatic steatosis in mice via a novel transcriptional cascade. Hepatology 59(5):1750-1760