Alexander Galazyuk, Ph.D.
- Associate Professor of Anatomy and Neurobiology
- Graduate Faculty Advsg Status College of Graduate Studies
I earned my bachelor’s degree at Kiev State University, Ukraine, in 1982, and then Ph.D. in Bogomoletz Institute of Physiology in Kiev, Ukraine in 1992. In 1994 I accepted a postdoctoral position at the Department of Molecular and Integrative Physiology at the University of Illinois at Urbana-Champaign, USA. In 2003 I accepted an appointment as Assistant Professor at the Northeast Ohio Medical University (NEOMED) in Rootstown, Ohio, where I am currently Professor of Anatomy and Neurobiology.
Throughout my career, I have been working in the field of auditory neuroscience. My research is mainly focused on the brain mechanisms underlying our ability to analyze precise timing information in sounds. While studying the response properties of auditory neurons to long-lasting sounds, we discovered that sound could suppress neuronal spontaneous activity for several seconds after a sound was presented.
Area of Expertise/Research Interests
METHODOLOGICAL APPROACHES USED IN MY RESEARCH
In my lab, we are using electrophysiological and behavioral approaches to study the auditory system. Electrophysiological approaches include but are not limited to extracellular and intracellular recordings of single-neuron responses at different levels of the central auditory system as well as non-auditory brain structures in unanesthetized animals. Behavioral approaches are mainly focused on tinnitus or hearing loss assessments in laboratory animals using pre-pulse inhibition of the acoustic startle reflex. Our lab was the first to develop a tinnitus mouse model which is widely used in the field of tinnitus research.
- Neurobiology (M1 Medical Students and Graduate Students)
- Cellular and Molecular Neuroscience (Graduate Students)
- Systems Neuroscience (Graduate Students)
- Kristaponyte I, Beebe NL, Young JW, Shanbhag SJ, Schofield BR, Galazyuk AV. (2021) Group II metabotropic glutamate receptors modulate sound evoked and spontaneous activity in the mouse inferior colliculus. eNeuro. 8(1):0328-20.
- Wilkinson GS, Adams DM, Haghani A, Lu AT, Zoller J, Breeze CE, Arnold BD, Ball HC, Carter GG, Cooper LN, Dechmann DKN, Devanna P, Fasel NJ, Galazyuk AV, Günther L, Hurme E, Jones G, Knörnschild M, Lattenkamp EZ, Li CZ, Mayer F, Reinhardt JA, Medellin RA, Nagy M, Pope B, Power ML, Ransome RD, Teeling EC, Vernes SC, Zamora-Mejías D, Zhang J, Faure PA, Greville LJ, Herrera M LG, Flores-Martínez JJ, Horvath S. (2021) DNA methylation predicts age and provides insight into exceptional longevity of bats. Nat Communication. 12(1): 1615.
- Galazyuk AV, Voytenko SV, Longenecker RJ, Kristaponyte I, Nelson GL (2019) Residual inhibition: From the putative mechanisms to potential tinnitus treatment. Hear Res. 375: 1-13.