Christine Dengler-Crish, Ph.D.
APPointments
- Assistant Professor, Department of Pharmaceutical Sciences
- Research Assistant Professor, Department of Anatomy & Neurobiology
- Graduate Faculty III, College of Graduate Studies
Bio
My lab’s research mission is to identify “presymptomatic” brain changes in Alzheimer’s disease, glaucoma, and related brain disorders, interrogate the mechanisms behind these changes, and develop innovative targets for therapeutic intervention. My research combines classic neuroanatomical, neuropharmacological, and comparative approaches with innovative new technology, and our methods include neuronal tract tracing, immunofluorescence, epifluorescent wide-field and confocal microscopy, advanced protein quantification techniques, and high-throughput bone densitometry. Our interdiscliplinary team of staff, students, and collaborators span a wide range of scientific backgrounds that include neuroscience, biology, chemistry, pharmacology, psychology, anatomy, electrophysiology, anatomy, toxicology, and translational research. This gives us an advantage in approaching the complex multidimensional nature of neurodegenerative disease.
Area of Expertise/Research Interests
Research Interests
- Presymptomatic neurodegenerative disease
Background Expertise
- Sensory neurobiology: somotosensory, visual, and gustatory systems
- Neuropharmacology
- Behavioral and systems neuroscience
- Neuroanatomy
- Human anatomy & physiology
- Phenotypic plasticity and reproductive biology of naked mole-rats
- Bone densitometry in rodents
- Research design and analysis (for both basic animal research and clinic-based human subjects populations)
Educational Background
- Ph.D. in Neuroscience, Vanderbilt University, Nashville, TN. 2008.
- M.A. in Behavioral Neuroscience, University of Illinois at Chicago, Chicago, IL. 2003.
- B.A. in Psychology, Baldwin Wallace University, Berea, OH. 1999.
Courses
- Human Anatomy & Physiology for Pharmacy (1st year pharmacy students)
- Transitions to Pharmaceutical Medicine (1st year graduate students)
- Foundational Neuroscience (1st year pharmacy students)
- Medical Neuroscience (1st year medical students)
- Pharmacotherapeutics III (3rd year pharmacy students)
