Heart & Blood Vessel Disease Research

Funded Research Proposals

Featured publications of the Heart and Blood Vessel Disease Research Focus Area include a selection of significant books, articles, and working papers published by our researchers.

Hausenloy DJ, Chilian W, Crea F, Davidson SM, Ferdinandy P, Garcia-Dorado D, van Royen N, Schulz R, and Heusch G. The coronary circulation in acute myocardial ischaemia/reperfusion injury – a target for cardioprotection. Cardiovasc Res 2018.

Jamaiyar A, Juguilon C, Dong F, Cumpston D, Enrick M, Chilian WM, and Yin L. Cardioprotection during Ischemia by Coronary Collateral Growth. Am J Physiol Heart Circ Physiol 2018.

Jamaiyar A, Wan W, Janota DM, Enrick MK, Chilian WM, and Yin L. The versatility and paradox of GDF 11. Pharmacol Ther 175: 28-34, 2017.

Jamaiyar A, Wan W, Ohanyan V, Enrick M, Janota D, Cumpston D, Song H, Stevanov K, Kolz CL, Hakobyan T, Dong F, Newby BZ, Chilian WM, and Yin L. Alignment of inducible vascular progenitor cells on a micro-bundle scaffold improves cardiac repair following myocardial infarction. Basic Res Cardiol 112: 41, 2017.

Kang PT, Chen CL, Lin P, Chilian WM, and Chen YR. Erratum to: Impairment of pH gradient and membrane potential mediates redox dysfunction in the mitochondria of the post-ischemic heart. Basic Res Cardiol 112: 49, 2017.

Kang PT, Chen CL, Lin P, Chilian WM, and Chen YR. Impairment of pH gradient and membrane potential mediates redox dysfunction in the mitochondria of the post-ischemic heart. Basic Res Cardiol 112: 36, 2017.

Kanugula AK, Adapala RK, Midha P, Cappelli HC, Meszaros JG, Paruchuri S, Chilian WM, and Thodeti CK. Novel noncanonical regulation of soluble VEGF/VEGFR2 signaling by mechanosensitive ion channel TRPV4. FASEB J 33: 195-203, 2019.

Lieder HR, Kleinbongard P, Skyschally A, Hagelschuer H, Chilian WM, and Heusch G. Vago-Splenic Axis in Signal Transduction of Remote Ischemic Preconditioning in Pigs and Rats. Circ Res 123: 1152-1163, 2018.

Mayorga ME, Kiedrowski M, McCallinhart P, Forudi F, Ockunzzi J, Weber K, Chilian W, Penn MS, and Dong F. Role of SDF-1:CXCR4 in Impaired Post-Myocardial Infarction Cardiac Repair in Diabetes. Stem Cells Transl Med 7: 115-124, 2018.

Ohanyan V, Sisakian H, Peketi P, Parikh A, and Chilian W. A chicken and egg conundrum: coronary microvascular dysfunction and heart failure with preserved ejection fraction. Am J Physiol Heart Circ Physiol 314: H1262-H1263, 2018.

Ohanyan V, Yin L, Bardakjian R, Kolz C, Enrick M, Hakobyan T, Luli J, Graham K, Khayata M, Logan S, Kmetz J, and Chilian WM. Kv1.3 channels facilitate the connection between metabolism and blood flow in the heart. Microcirculation 24: 2017.

Pung YF, Chilian WM, Bennett MR, Figg N, and Kamarulzaman MH. The JCR:LA-cp rat: a novel rodent model of cystic medial necrosis. Am J Physiol Heart Circ Physiol 312: H541-H545, 2017.

Shi X, Zhang W, Yin L, Chilian WM, Krieger J, and Zhang P. Vascular precursor cells in tissue injury repair. Transl Res 184: 77-100, 2017.

Yin L, Chilian WM, and Dong F. Epigenetic regulation in diabetes-associated oxidative stress and myocardial dysfunction. Int J Cardiol 268: 193-194, 2018.

Rituparna Ganguly, Soumyadip Sahu, Vahagn Ohanyan, Rebecca Haney, Ronaldo Chavez, Shivani Shah, Siri Yalamanchili and Priya Raman* (2017) Oral chromium picolinate impedes hyperglycemia-induced atherosclerosis and proatherogenic protein TSP-1 expression in STZ-induced type 1 diabetic ApoE-/- mice.  Scientific Reports 7: 45279.

Sahu, S., Ganguly, R. and Raman, P*.  (2016) Leptin augments recruitment of IRF-1 and CREB to Thrombospondin-1 Gene Promoter in Vascular Smooth Muscle Cells in vitro.  Am. J Physiol. Cell Physiol. Published 8 June 2016, Vol 311, No. 2: C212-C224, DOI: 10.1152/ajpcell.00068.2016.

CONTACT

William M. Chilian, Ph.D.
Director, Heart & Blood Vessel Disease Research Area
Phone: 330.325.6426
Email: wchilian@neomed.edu

HEART & BLOOD VESSEL DISEASE RESEARCH

Research Focus Area at NEOMED