Research & Faculty

Summer Research Fellowship Program

The Summer Research Fellowship Program is a mentored research program, designed to:

  • provide you with intensive training in research procedures and principles in basic and clinical disciplines
  • enhance your research horizons
  • develop scientific presentation and writing skills
Important Dates
  • April 28, 2017: Deadline to apply

 

2017 Opportunities

View the project investigators, their project titles and a brief overview below. For more detailed information or to apply for the program download the project catalog [PDF].

Anatomy & Neurobiology

Assistant Professor of Anatomy and Neurobiology
Email: lcooper@neomed.edu

Project Title
Molecular Regulation of Bone Phenotype in Bats and Mice

Overview
The objective of this study is to characterize the in vivo and in vitro differences in expression patterns for genes critical to bone development, maintenance and remodeling in bats and mice. Based on preliminary data, the working hypothesis for this study is that bats, compared to mice, display novel in vivo and in vitro bone cell signaling and activity rates in those genes crucial for bone deposition and remodeling.

Professor of Anatomy and Neurobiology
Email: rgerman@neomed.edu

Project Title
The Effect of Preterm Birth and RLN Damage on Airway Protection and Maturation

Overview
To create an animal model to measure the coordination between respiration and swallowing in infants, and test the impact (1) of prematurity, (2) RLN sensory damage, and (3) the recovery and maturation over time of that coordination. We will them precisely measure the pathoneurophysiology causing dysphagia. Data will be collected that will address three larger goals and used to test a number of specific hypotheses associated with the goals.

Associate Professor of Anatomy and Neurobiology
Email: dpeterson@neomed.edu

Project Title
Histology Across the Human Lifespan: A Photographic Atlas Project

Overview
This project will continue the development of an educational resource for students of higher education pursuing coursework in basic medical science programs.

Assistant Professor of Anatomy and Neurobiology
Email: mrosen@neomed.edu

Project Title
The interactive effects of development stress and hearing loss on auditory perceptual abilities

Overview
Does early stress worsen perceptual deficits induced by early hearing loss, and is this effect due to synergistic changes at the level of auditory cortex?

Professor of Anatomy and Neurobiology
Email: fayez.safadi@neomed.edu

Project Title
Comparison between Osteoactivin and Bone Morphogenetic Protein-2 in Rat Spinal Fusion Model

Overview
The goal of this project is to assess direct comparison between OA and BMP-2 in rat spinal fusion model. We will specifically focus on 1) motion at the L4-5 segment after fusion surgery, 2) high resolution radiography assessing bone mass, 3)uCT assessment of the fusion looking at multiple parameters, 4) histologic studies, and 5) biomechanical strength of the fusion. We will also include assessing systemic effects of each treatment by comparing general data including complete metabolic panel, complete blood count with differential, and histology of other organ systems.

Research Assistant Professor
Email: sshanbhag@neomed.edu

Project Title
Brain Circuitry and Neurochemistry Underlying Hearing and Emotions

Overview
The long term goal is to improve the understanding of neural mechanisms that underlie acoustic communication. The specific aim of this project is to identify and quantify the neurochemicals responsible for contextual modulation in the amygdala.

Professor of Anatomy and Neurobiology
Email: cvinyard@neomed.edu

Project Title
Gross Anatomy Multimedia Development

Overview
Assist with the development and implementation of multimedia teaching resources for the NEOMED Yassine Gross Anatomy Laboratory. Specifically, the fellow will have the opportunity to assist in creating a virtual dissector, developing medical imaging for specific dissection experiences, developing videos for use in the lab and learning the pedagogical basis for multimedia content delivery.

Professor and Chair of Anatomy and Neurobiology
Email: jjw@neomed.edu

Project Title
The role of social context in vocal behavior

Overview
The goal is to characterize social interactions between bats in order to understand how social context influences the processing of bat vocalizations.

Family & Community Medicine

Associate Professor of Family & Community Medicine
Email: kbaughma@neomed.edu

Project Title
Pilot Study Exploring Advance Care Planning Values of African American Community Members

Overview
To examine the values and circumstances of African American adults that influence end-of-life decisions so that physicians can better engage patients in advance care planning (ACP). ACP is the ongoing process of discussions between patients, family members, and health care providers about the patient’s preferences for health care treatments for when they are no longer able to communicate those wishes.

Chair, Department of Family and Community Medicine
Email: jboltri@neomed.edu

Project Title
Primary Care Training and Enhancement at Residency Programs

Overview
This project measures practice transformations, techniques for reducing health disparities, population health management, and primary care provider quality of life implementation at residency programs.

Project Title
Identifying Interprofessional Team-Based Learning in Federally Qualified Health Centers

Overview
Determine resources and challenges to implementing the Area Health Education Center (AHEC) Scholars Program in northeastern Ohio.

Professor and Director of Consortium of Eastern Ohio Master of Public Health
Email: afl@neomed.edu

Project Title
Defining the Opiate Problem in Carroll County

Overview
To develop a foundation for understanding the opiate problem in Carroll county. Special considerations include understanding adolescent issues with opiates, what would be effective programming, and barriers to treatment. This preliminary study into the problem would be used to develop a more comprehensive survey to look at opiate addiction more closely in the county in the future.

Assistant Professor of Family and Community Medicine
Email: mbs@neomed.edu

Project Title
Qualitative Analysis of 3rd Year Medical Students’ Hospice Experience Narratives

Overview
The primary goal of the hospice experience is for students to learn about humanistic issues from the perspective of a hospice patient and family.

Assistant Professor of Family and Community Medicine
Email: gweisblat@neomed.edu

Project Title
Pipeline Program Typology Tool

Overview
Finish the Typology Scale documenting each component in literature, and build a process and evaluation structure that will test the new tool that reflects a mixed-methods approach.

Integrative Medical Sciences

Assistant Professor
Email: ibratz@neomed.edu

Project Title
Requisite Rold for TRPV1 in Gastrointenstinal Function

Overview
Diet-induced obesity detrimentally affects hepatic function with respect to both metabolic and circadian homeostasis. This study will explore the molecular pathways by which diet-induced disrupts rhythms, which must be critically maintained in the liver to control lipid, glucose and bile homeostasis, thus leading to non-alcholic fatty liver disease. The focus of this research will be honed on Cyp7a1, the rate-limiting enzyme that converts cholesterol to bile acids. Cyp7a1 expression, and consequently bile acid content, are controlled by nutrient regulation, circadian rhythms, and negative feedback by bile acids themselves.

Professor of Integrative Medical Sciences
Email: 
ychen1@neomed.edu

Project Title
Mitochondrial proteomics in the disease of myocardial infarction

Overview
To assess the role of complex III impairment in the pathogenesis of myocardial infarction and to explore new insights into the specific disease biomarker of mitochondria in order to more fully understand the mechanisms of cardiovascular disease.

Professor and Chair of Integrative Medical Sciences
Email: wchilian@neomed.edu

Project Title
Is HFpEF (Heart Failure with Preserved Ejection Fraction) Caused by Coronary Microvascular Disease?

Overview
The goal of this proposal is to answer the question, do impairments in the connection between myocardial blood flow and cardiac work (ie: insufficient dilation to match the metabolic needs of working cardiac muscle) cause a condition known as HFpEF?

Associate Professor of Biochemistry and Molecular Pathology

Project Title
The human CYP4F2 fatty acid omega hydroxylase in the prevention of inflammation and progression of fatty liver disease.

Overview
The goal of this research is to determine the role of human CYP4F2 gene in the prevention of inflammation and progression of fatty liver disease. The objective of this proposal is to determine if increased in vivo hepatic expression of CYP4F2 gene in the ear model of inflammation decreases LTB4 induced ear swelling and immune cell recruitment. A second objective is to determine if the in vivo hepatic expression of CYP4F2 genes decreases triglyceride storage and pro-inflammatory LTB4 levels and prevents neutrophil recruitment in the liver of mice fed a high fat diet.

Associate Professor of Integrative Medical Sciences
Email: lyin@neomed.edu

Project Title
Mechanism of Coronary Collateral Growth

Overview
The overarching goal of this research is to stimulate the growth of coronary collaterals by combination of genes therapy stem cell therapy in patients so they can grow their own bypasses as a treatment for ischemic heart disease.

Associate Professor of Integrative Medical Sciences
Email: yzhang@neomed.edu

Project Title
The Role of Human Carboxylesterases in Alcoholic Liver Diseases

Overview
We will investigate whether human CES1, CES2 or CES3 plays a role in the pathogenesis of ALD and the underlying mechanism.

Pharmaceutical Sciences

Assistant Professor
Email: ccrish@neomed.edu

Project Title
Serotonin deficits in the raphe and bone loss in Alzheimer’s disease

Overview
Identify deficits in regional expression of serotonin markers in the raphe nuclei and hippocampus of two AD mouse models representing different dominant Alzheimer’s pathologies.

Assistant Professor of Pharmaceutical Sciences
Email: sfleming1@neomed.edu

Project Title
Gene-Environment Interactions in Parkinson’s Disease

Overview
The goal of these studies is to understand the role of ATP13A2 in cellular dysfuction and neurodegeneration. The objective is to characterize ATP13A2 x enviromental exposure interactions and determine the mechanisms by which they contribute to behavioral dysfunction and neurodegeneration in vivo.

Assistant Professor of Pharmaceutical Sciences
Email: mhossain@neomed.edu

Project Title
Pesticide Exposure and Adult Hippocampal neurogenesis

Overview
To identify the precise stages of hippocampal neurogenesis disprupted by deltamethrin exposure.

Assistant Professor of Pharmaceutical Sciences
Email: dinman@neomed.edu

Project Title
Mitochondrial trafficking deficit in glaucoma-related neurodegeneration

Overview
The objective is to evaluate mitochondria movement and dynamics, calcium regulation and axon transport with and without exposure to hydrostatic pressure.

Assistant Professor of Pharmaceutical Sciences
Email: tkasumov@neomed.edu

Project Title
The mechanism of ceruloplasmin/myeloperoxidase dysfunction under oxidative stress in non-alcoholic fatty liver disease

Overview
Apply mass spectrometry-based immunoprecipitation proteomics to determine whether the modification of CP can potentially lead to its dysfuction and thus aggravated oxidative stress due to inefficient MPO peroxidase inhibition in NAFLD patients. The objective of this project is to efficiently enrich CP variants from human serum (aim 1), detect Y904 nitration in serum samples (aim 2), and investigate the effect of this modification of CP function and stability (aim 30).

Assistant Professor of Pharmaceutical Sciences
Email: moyewumi@neomed.edu

Project Title
Development of a Lyophilization Process for Polymersomes Loaded with a Model Protein Drug

Overview
The project is an important aspect of ongoing research in my lab that is focused on development of nano-scale delivery systems for protein-based therapeutics that can be applied in the treatment of neurological diseases.

Professor of Pharmaceutical Sciences
Director of Neurodegenerative Disease and Aging Research Focus Area
Email: jrichardson@neomed.edu

Project Title
Repositioning Drugs for Neuroprotection in Parkinson’s Disease

Overview
The goal of this project will be to determine whether zonisamide treatment can protect from dopamine neuron loss in two animal models of PD.

Psychiatry

Assistant Professor
Email: nbonfine@neomed.edu

Project Title
Barriers and Facilitators to Cross-System Collaboration: Assessing Stakeholder Perspective of Sequential Intercept Mapping

Overview
Anecdotal evidence suggest that the Sequential Intercept Mapping process helps community members come together. This research project will expand upon the work of this evaluation by looking at the ability of cross-systems stakeholders to collaborate effectively. This understanding may improve the implementation of the process within communities, and ultimately inform the field more broadly about the steps necessary to gain cross-system collaboration to address the overpresentation of mental illness in the justice system.

Questions? Please Contact:

Nona Hose
Executive Administrative Assistant
Phone: 330.325.6499
Email: nhose@neomed.edu

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