Yanqiao Zhang, M.D. Lab
Dr. Yanqiao Zhang, Associate Professor
My laboratory is interested in understanding the role of both transcription factors and non-transcription factors in controlling lipid and carbohydrate homeostasis and obesity. We are particularly interested in the nuclear receptors FXR (farnoesoid X receptor) and HNF4α (hepatocyte nuclear factor 4α).
These two nuclear receptors play important roles in regulating bile acid, lipid and glucose metabolism. One of our recent research interests has been to study the role of hepatic non-transcriptional factors (such as carboxylesterase 1) in regulating lipid and carbohydrate metabolism and obesity.
We have been utilizing transgenic and knockout mouse models, together with biochemical, molecular and cellular, and pharmacological approaches, to complete our studies.
Dr. Yuanyuan Li and Dr. Yanyong Xu, postdoctoral fellows
Dr. Yang Xu, postdoctoral fellow
Kavita Jadhav, graduate student