Yanqiao Zhang, M.D. Lab
Dr. Yanqiao Zhang, Associate Professor
My laboratory is interested in understanding the role of both transcription factors and non-transcription factors in controlling lipid and carbohydrate homeostasis and obesity. We are particularly interested in the nuclear receptors FXR (farnoesoid X receptor) and HNF4α (hepatocyte nuclear factor 4α).
These two nuclear receptors play important roles in regulating bile acid, lipid and glucose metabolism. One of our recent research interests has been to study the role of hepatic non-transcriptional factors (such as carboxylesterase 1) in regulating lipid and carbohydrate metabolism and obesity.
We have been utilizing transgenic and knockout mouse models, together with biochemical, molecular and cellular, and pharmacological approaches, to complete our studies.
Dr. Yuanyuan Li and Dr. Yang Xu, postdoctoral fellows
Kavita Jadhav and Jiesi Xu, graduate students
Dr. Yanqiao Zhang and graduate student, Jiesi Xu