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June Yun Ph.D.

Associate Professor of Molecular Pharmacology

Integrative Medical Sciences

 

Phone: (330)325-6412

Location: RGE-337

jyun@neomed.edu

 

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June Yun, Ph.D.

Associate Professor of Physiology and Pharmacology
Department of Integrative Medical Sciences
College of Medicine

Education

Ph.D., The George Washington University, Washington, D.C./The National Institutes of Health, Bethesda, Md. - 2001

B.S., The Ohio State University, Columbus, Ohio - 1994

Professional Experience

Associate Professor of Physiology and Pharmacology, Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, Ohio - 2014-Present

Assistant Professor of Physiology and Pharmacology, Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, Ohio - 2003-2014

Research Associate, Department of Molecular Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio -  2003

Postdoctoral Research Fellow, Department of Molecular Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio -2001-2003

Recent Publications

Dr. Yun's publications listed in PubMed.

Li T, Varadarajulu S, Beard LL, Yun J, Folkesson HG. A noninflammatory interleukin-1beta fragment stimulates fetal lung fluid absorption in guinea pigs. J Pharmacol Exp Ther. 2007 Feb;320(2):877-84. Epub 2006 Nov 15. PMID: 17108236

Yun J, Rocic P, Pung YF, Belmadani S, Carrao AC, Ohanyan V, Chilian WM.  Redox-dependent mechanisms in coronary collateral growth: the "redox window" hypothesis. Antioxid Redox Signal. 2009 Aug;11(8):1961-74. Review.  PMID:19416057

Carrão AC, Chilian WM, Yun J, Kolz C, Rocic P, Lehmann K, van den Wijngaard JP, van Horssen P, Spaan JA, Ohanyan V, Pung YF, Buschmann I.  Stimulation of coronary collateral growth by granulocyte stimulating factor: role of reactive oxygen species. Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1817-22. Epub 2009 Jun 18. PMID:19542022

Kang PT, Yun J, Kaumaya PP, Chen YR. Design and use of peptide-based antibodies decreasing superoxide production by mitochondrial complex I and complex II. Biopolymers. 2011;96(2):207-21. PMID: 20564035

B. Rorabaugh, J. Yun, and D.M. Perez. Microarray Analysis of Novel Adrenergic Receptor Functions. In: The Adrenergic Receptors in the 21st Century: The Receptor Series. Volume Editor: Dianne M. Perez: Series Editor: Kim Neve. Humana Press, Inc., 2005.

P. Kammermeier, and J. Yun. Activation of metabotropic glutamate receptor 1 dimers requires glutamate binding in both subunits. J. Pharmacol. Exp. Ther. 2004. 312: 502-508.

B. Rorabaugh, J. Yun, and D.M. Perez. Microarray Analysis of Novel Adrenergic Receptor Functions. In: The Adrenergic Receptors in the 21st Century: The Receptor Series. Volume Editor: Dianne M. Perez: Series Editor: Kim Neve. Humana Press, Inc., 2004.

K. Sangkuhl, A. Schulz, H. Rompler, J. Yun, J. Wess, T. Schoneberg. Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo. 2004. Hum. Mol. Genet. 13: 893-903.

P.J. Gonzalez-Cabrera, J. Yun, D.F. McCune, B.R. Rorabaugh, and D.M. Perez. Differential regulation of the cell cycle by α1-adrenergic receptor subtypes. 2004. Endocrinology. 2004 Nov;145(11):5157-67. Epub 2004 Aug 5.

J. Yun, R.J. Gaivin, A. Boongird, Z. Ying, P.J. Gonzalez-Cabrera, R.S. Papay, I. Najm, and D.M. Perez. Gene expression profile of age-progressive neurodegeneration induced by ?1B-adrenergic receptor overactivity: NMDA/GABAA dysregulation. 2003. Brain. 126: 2667-2681.

S.A. Ross, D. Chalothorn, J. Yun, P.J. Gonzalez-Cabrera, D.F. McCune, B. Rorabaugh, M.T. Piascik, and D.M. Perez. The alpha(1B)-adrenergic receptor decreases the inotropic response in the mouse Langendorff heart model. 2003. Cardiovasc. Res, 60: 598-607.

P.J. Gonzalez-Cabrera, R. Gaivin, J. Yun, S.A. Ross, R.S. Papay, D.F. McCune, B.R. Rorabaugh, and D.M. Perez. Genetic Profiling of alpha(1)-Adrenergic Receptor Subtypes by Oligonucleotide Microarrays: Coupling to Interleukin-6 Secretion but Differences in STAT3 Phosphorylation and gp-130. 2003. Mol. Pharmacol. 63:1104-1116.

J. Yun, M.J. Zuscik, D.F. McCune, P. Gonzalez-Cabrera, M.T Piascik, and D.M. Perez. Identification of src-related growth, apoptotic, and inflammatory responses in α1B-adrenergic receptor-induced cardiac hypertrophy. 2003. Cardiovasc. Res. 57: 443-455.