Skip to content. | Skip to navigation

Personal tools
Log in
Sections
Gary Mezaros.JPG

Gary Meszaros Ph.D.

Associate Professor of Physiology and Pharmacology

Integrative Medical Sciences

 

Phone: (330)325-6432

Location: RGE-344

 

View Laboratory Website

Download Headshot


J. Gary Meszaros, Ph.D.

Associate Professor of Physiology and Pharmacology
Department of Integrative Medical Sciences
College of Medicine
jgmeszar@neomed.edu

Education

Ph.D., University of Texas Health Science Center at Houston, Texas - 1996

B.A., College of Wooster, Ohio - 1989

Professional Experience

Associate Professor of Physiology and Pharmacology, Northeast Ohio Medical University, Rootstown, Ohio - 2007-Present 
Research Focus: Cellular mechanisms of cardiac remodeling and fibrosis
Teaching Focus: Endocrine Physiology and Cellular Signaling

Assistant Professor of Physiology and Pharmacology, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio -  2000-2007

Postdoctoral Fellow, University of California San Diego, San Diego, California - 1996-2000

Doctoral Student, University of Texas Health Science Center at Houston, Graduate School of Biomedical Sciences, Houston, Texas - 1991-1996

Research Assistant, Baylor College of Medicine, Houston, Texas - 1989-1991

Research Assistant, Cleveland Clinic Foundation, Cleveland, Ohio - 1989

Recent Publications

Dr. Meszaros' publications listed in PubMed

Luther DJ, Thodeti CK, Shamhart PE, Adapala RK, Hodnichak C, Weihrauch D, Bonaldo P, Chilian WM, Meszaros JG. (2012).  Absence of type VI collagen paradoxically improves cardiac function, structure, and remodeling after myocardial infarction. Circ Res. 2012 Mar 16;110(6):851-6. Epub 2012 Feb 16. (PMID: 22343710)

Ohanyan VA, Guarini G, Thodeti CK, Talasila PK, Raman P, Haney R, Meszaros JG, Damron DS, Bratz IN.  (2011).  Endothelin Mediated In Vivo Pressor Responses following TRPV1 Activation. Am J Physiol Heart Circ Physiol. [Epub ahead of print]

Adapala RK, Talasila PK, Bratz IN, Zhang DX, Suzuki M, Meszaros JG, Thodeti CK.  (2011).  PKC{alpha} mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells. Am J Physiol Heart Circ Physiol. [Epub ahead of print]

Shamhart, P.E. and J.G. Meszaros. (2010).  Non-fibrillar collagens: Key mediators of post-infarction cardiac remodeling? J. Mol. Cell Cardiol. (Invited Review) 48:530-537.

Luther, D.J., Ohanyan, V., Shamhart, P.S., Hodnichak, C.M., Hamayak, S., Booth, T.D., Meszaros, J.G., and A. Bishayee (2010).  Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma.  Investigational New Drugs 29:380-91.

Shamhart, P.E., Luther, D.J., Hodson, B.R., Koshy, J.C., Ohanyan, V. and J.G. Meszaros (2009).  Impact of type 1 diabetes on cardiac fibroblast activation: enhanced cell cycle progression and reduced myofibroblast content in diabetic myocardium. Am. J. Physiol. Endocrinol. Metab. In press (PMID: 19706787).

Luther, D.J., Ohanyan, V., Shamhart, P.S., Hodnichak, C.M., Hamayak, S., Booth, T.D., Meszaros, J.G., and A. Bishayee (2009). Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma. Investigational New Drugs, In press, MS#DRUG468.

Shamhart, P.E. and J.G. Meszaros (2009). Non-fibrillar collagens: Key mediators of post-infarction cardiac remodeling? J. Mol. Cell Cardiol. (Invited Review). In press (PMID: 19573533).

Maron, M.B., Luther, D.J., Pilati, C.F., Ohanyan, V., Li T., Koshy, S., Horne, W.I., Meszaros, J.G., Walro, J.M. and H.G. Folkesson. (2009).  Beta-adrenoceptor stimulation of alveolar fluid clearance is increased in rats with heart failure. Am. J. Physiol. Lung Cell. Mol. Physiol. 297:L487-95.

Bryant, J.E., Shamhart, P.E., Luther, D.J., Olson, E.R., Koshy, J.C., Costic, D.J., Mohile, M.V., Dockry, M., Doane, K.J., and J.G. Meszaros (2009). Cardiac myofibroblast differentiation is attenuated by a3 integrin blockade: potential role in post-MI remodeling. J. Mol. Cell Cardiol. 46:186-192.

Olson, E.R., Shamhart, P.E., Naugle, J.E., and J.G. Meszaros (2008). Angiotensin II-induced ERK1/2 activation is mediated by PKCd and intracellular calcium in adult rat cardiac fibroblasts. Hypertension 51:704-711.

Grobe, J.L., Der Sarkissian, S., Lihui, Y., Stewart, J.M., Meszaros, J.G., Raizada, M.K., and M.J. Katovich (2007). ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts. Clin. Sci. (Lond). 113:357-364.

Jenkins, C., Milsted, A., Doane, K., Meszaros, G., Toot, J., and D. Ely (2007). A cell culture model using rat coronary artery adventitial fibroblasts to measure collagen production. BMC Cardiovasc. Disord. 7:13.

Naugle, J.E., Olson, E.R., Zhang, X., Mase, S.E., Pilati, C.F., Maron, M.B., Folkesson, H.G., Horne, W.I, Doane, K.D and J.G. Meszaros (2006). Type VI collagen induces cardiac myofibroblast differentiation: implications for post-infarction remodeling. Am. J. Physiol. Heart and Circ. Physiol. 290:H323-330.

Olson, E.R., Naugle, J.E., Zhang, X., and Bomser, J.A. and J.G. Meszaros (2005). Inhibition of cardiac fibroblast proliferation and myofibroblast differentiation by resveratrol. Am. J. Physiol. Heart and Circ. Physiol. 288:H1131-1138.

Swaney, J., Naugle, J.E., Olson, E.R., Meszaros, J.G., Roth, D., and P.A. Insel (2005). Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylyl cyclase. Proc. Natl. Acad. Sci. 102:437-442.

Invited Editorship

Editor, Medical Student Study Guide (2006): Crash Course in Endocrine and Reproductive Systems.  (Editors:  J. Gary Meszaros, Stephan Sanders, Jennifer E. Naugle and Erik R. Olson), Elsevier Press, London.

Invited Book Chapters Published

Epperson, S., Gustafsson, A, Gonzalez, A.M., Villegas, S., Meszaros, J.G., and L.L. Brunton.  (2004). Pharmacology of G-protein-linked signaling in cardiac fibroblasts, in Interstitial Fibrosis in Heart Failure (editor: F.J. Villarreal), Springer Press, New York.

Meszaros, J.G., Brunton, L.L., and Bloor, C.M. (1998).  Animal Models of Angiogenesis in Cardiovascular Tissues, in Angiogenesis and Cardiovascular Disease (editors: J. Ware and M. Simons), Oxford Press, London.