Schofield Lab Projects
Functional Anatomy of the Auditory Pathways
Principal Investigator: Brett Schofield
Funding source: National Institute on Deafness and other Communication Disorders
This project focuses on the inferior colliculus (IC), a major auditory center in the midbrain. There are two main areas of investigation, each focused on a specific neurotransmitter:
1. GABA is a major inhibitory neurotransmitter in the IC. Our first area of interest is to identify relationships between descending auditory pathways and GABA-using cells in the IC.
2. Acetylcholine (ACh) is a neurotransmitter involved in arousal, sleep/wake cycles, and neural plasticity. Our second area of interest is to identify cells that use ACh and to characterize their connections with IC cells and with descending auditory pathways.